Dry AMD is characterized by which of the following?

Dry AMD is characterized by which of the following?

• A. Drusen above Bruch's membrane causing gradual vision loss
• B. Drusen within the macula above Bruch's membrane causing gradual loss
• C. Wet AMD involves neovascularization
• D. Central retinal detachment

Answer: (B)

Dry AMD shows drusen—extracellular deposits—in the sub-RPE space, specifically in the macula, which lie between the retinal pigment epithelium and Bruch's membrane. This accumulation disrupts RPE function and leads to gradual, progressive central vision loss. The best description here is drusen within the macula above Bruch's membrane causing gradual loss. Wet AMD, by contrast, involves choroidal neovascularization with leakage and faster vision decline, and central retinal detachment is a separate condition.

Dry AMD shows drusen—extracellular deposits—in the sub-RPE space, specifically in the macula, which lie between the retinal pigment epithelium and Bruch's membrane. This accumulation disrupts RPE function and leads to gradual, progressive central vision loss. The best description here is drusen within the macula above Bruch's membrane causing gradual loss. Wet AMD, by contrast, involves choroidal neovascularization with leakage and faster vision decline, and central retinal detachment is a separate condition.