Which statement best differentiates Wet AMD from Dry AMD?

Which statement best differentiates Wet AMD from Dry AMD?

• A. Wet AMD involves abnormal choroidal vessels that leak under the macula; Dry AMD involves drusen and slower progression
• B. Dry AMD involves abnormal vessels that leak
• C. Wet AMD has no central vision loss
• D. Dry AMD progresses faster than Wet AMD

Answer: (A)

The key concept here is how the two AMD types differ in their underlying pathology. Wet AMD is driven by abnormal choroidal vessels that grow under the macula and leak fluid or blood, leading to rapid vision changes. Dry AMD, on the other hand, is characterized by drusen deposits with slower, gradual progression toward geographic atrophy, without the CNV leakage seen in Wet AMD. So the statement that Wet AMD involves abnormal leaking choroidal vessels under the macula and that Dry AMD involves drusen with slower progression captures the fundamental difference. The other choices don’t fit: Dry AMD does not involve leaking vessels; Wet AMD can cause central vision loss; and Dry AMD does not progress faster than Wet AMD.

The key concept here is how the two AMD types differ in their underlying pathology. Wet AMD is driven by abnormal choroidal vessels that grow under the macula and leak fluid or blood, leading to rapid vision changes. Dry AMD, on the other hand, is characterized by drusen deposits with slower, gradual progression toward geographic atrophy, without the CNV leakage seen in Wet AMD. So the statement that Wet AMD involves abnormal leaking choroidal vessels under the macula and that Dry AMD involves drusen with slower progression captures the fundamental difference. The other choices don’t fit: Dry AMD does not involve leaking vessels; Wet AMD can cause central vision loss; and Dry AMD does not progress faster than Wet AMD.